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Altura (Wood, 2014)

TÍTULO DE ESTUDIO: Definiendo el papel de la variación común en la arquitectura genómica y biológica de la estatura humana adulta

TÍTULO DE ESTUDIO: Identificación en todo el genoma de 687 variantes asociadas a la altura.

VISIÓN DE CONJUNTO:  En los últimos 150 años, la altura promedio de los humanos ha aumentado alrededor de 4 pulgadas. Mientras que los factores ambientales como la nutrición tienen una fuerte influencia en el crecimiento del cuerpo humano, está claro que la altura es un rasgo altamente hereditario. De hecho, se cree que hasta 80% de la altura de una persona está determinada genéticamente. Sin embargo, la altura es un rasgo muy complejo influenciado por muchas variantes a lo largo del genoma. Para identificar las variantes genéticas asociadas a la altura, este estudio examinó a más de 250.000 individuos de ascendencia europea. Los investigadores descubrieron 697 variantes genéticas asociadas a la altura. En conjunto, estas variantes explican ~ 16% de las diferencias de altura observadas entre las personas. Algunas de las variantes identificadas están cerca de genes que están involucrados en el desarrollo de huesos y cartílagos.

¿SABÍAS? A partir de los 40 años, muchas personas comienzan a perder altura. Esto puede deberse a múltiples factores, como la compresión espinal relacionada con la edad y trastornos como la osteoporosis. El ejercicio y una nutrición saludable (que incluya mucho calcio) pueden ayudar a mantener huesos y músculos fuertes y limitar la pérdida de altura. [FUENTE]

RESULTADOS DE LA MUESTRA: Aprenda más sobre el Biblioteca de investigación de nebulosa.

resultados de la muestra de altura humana

VARIANTES ANALIZADAS: rs724016, rs7692995, rs3791679, rs8756, rs143384, rs798497, rs3760318, rs806794, rs4896582, rs720390, rs4369779, rs3814333, rs3825199, rs12214804, rs552707, rs2079795, rs1155939, rs9292468, rs10859567, rs9392918, rs17556750, rs314263, rs1074683, rs4733724, rs7701414, rs3811958, rs2284746, rs42039, rs1036821, rs9428104, rs7870753, rs7652177, rs2093210, rs12538407, rs5742915, rs9650315, rs2289195, rs3118905, rs1884897, rs9967417, rs991967, rs3800461, rs2871865, rs4986172, rs1367226, rs11049611, rs1812175, rs4548838, rs4735677, rs1535466, rs16942341, rs7033487, rs10748128, rs10958476, rs7849585, rs4448343, rs2854207, rs526896, rs961014, rs11880992, rs7466269, rs2974438, rs16860216, rs6439168, rs2856321, rs11684404, rs6696239, rs6894139, rs1401795, rs4337252, rs9993613, rs6714546, rs181338, rs11144688, rs17450430, rs1681630, rs817300, rs862034, rs9217, rs1815314, rs4974480, rs606452, rs9328445, rs7043114, rs994533, rs1950500, rs9835332, rs1923367, rs12330322, rs2573625, rs10770705, rs7740107, rs10948222, rs7980687, rs310421, rs6902771, rs7716219, rs897080, rs2806561, rs3807931, rs2280470, rs10780910, rs6600365, rs4620037, rs4803468, rs9880211, rs7154721, rs3020418, rs422421, rs12474201, rs12209223, rs7027110, rs1582931, rs7731703, rs12347744, rs509035, rs584828, rs7733195, rs7534365, rs12470505, rs2074977, rs12639764, rs2278483, rs1047014, rs6955948, rs6577717, rs1659127, rs10990303, rs6974574, rs7551732, rs227724, rs301901, rs13177718, rs6920372, rs11648796, rs2888877, rs2421992, rs822531, rs2597513, rs1325596, rs648831, rs2413143, rs7971536, rs291979, rs4072910, rs6879260, rs2390151, rs3958122, rs12779328, rs2237886, rs6540834, rs2956605, rs2028067, rs17511102, rs16859517, rs2425163, rs10152591, rs564914, rs7899004, rs763318, rs4652773, rs425277, rs39623, rs975210, rs8052560, rs2013265, rs7605699, rs1233627, rs2338115, rs10119624, rs2306694, rs4246302, rs6761041, rs4812586, rs1415701, rs8180991, rs8073371, rs955748, rs17081935, rs7745166, rs4273857, rs2581830, rs7162542, rs3790086, rs3782089, rs4332428, rs2302580, rs891088, rs1329393, rs7126398, rs11867479, rs11633371, rs10883563, rs318095, rs749052, rs9816693, rs7319045, rs8006657, rs1562975, rs2377058, rs6903448, rs10843390, rs2857693, rs2834442, rs4601530, rs1265097, rs7853235, rs13088462, rs6594336, rs4428898, rs7561273, rs6457374, rs3767627, rs10767838, rs12204421, rs2070776, rs16895130, rs6485978, rs632124, rs7112925, rs17792664, rs3923086, rs1550162, rs12882130, rs11221442, rs1935157, rs757081, rs11880124, rs17391694, rs1599473, rs1405212, rs17603945, rs17721822, rs4640244, rs3014219, rs991946, rs3885668, rs6733349, rs12411277, rs2305833, rs6441170, rs6921207, rs7517682, rs1257763, rs1326023, rs12344396, rs389663, rs9456307, rs7568069, rs1753637, rs2072153, rs12904334, rs3809790, rs9889755, rs7177711, rs9404952, rs2211866, rs6694089, rs11659752, rs2300921, rs1864439, rs1190545, rs1980850, rs4246079, rs9766, rs3812591, rs26868, rs1809889, rs10877030, rs1658351, rs2811594, rs9409082, rs17807185, rs3812040, rs17163588, rs7567288, rs26024, rs11687941, rs34651, rs11599750, rs6899744, rs10131337, rs989393, rs540652, rs2123731, rs711245, rs13078528, rs2687950, rs3957165, rs1529701, rs10863936, rs11152213, rs6751657, rs316618, rs12120956, rs12855, rs4686904, rs3812423, rs10880969, rs4834927, rs10790381, rs6845999, rs12987566, rs16834765, rs2631676, rs17369123, rs354196, rs7567851, rs2378870, rs12323101, rs1546391, rs6919534, rs2510396, rs12125882, rs3828760, rs2781373, rs7273787, rs12926008, rs2257011, rs33852, rs902143, rs17032525, rs10794175, rs11047239, rs6988484, rs17806888, rs212524, rs6949739, rs4901537, rs8103068, rs8102380, rs12186664, rs1625895, rs9443804, rs8017130, rs7659107, rs1742829, rs2240919, rs4656220, rs780094, rs11745439, rs6838153, rs11175992, rs9434723, rs1832871, rs4240326, rs13006748, rs932445, rs568610, rs4320932, rs1996422, rs7069985, rs4425077, rs2662027, rs4239020, rs17574650, rs479744, rs6561319, rs3739707, rs1341278, rs2072268, rs11677466, rs2145357, rs3129254, rs2306596, rs6420435, rs7834383, rs7727731, rs17349981, rs7985356, rs13393800, rs12458127, rs165189, rs4868126, rs1036477, rs2149163, rs4802134, rs10152739, rs567401, rs8067165, rs3763631, rs10495098, rs12435366, rs4953951, rs17088184, rs32855, rs4357716, rs6085662, rs2509133, rs7774834, rs12693589, rs2044124, rs8058684, rs429433, rs17122659, rs2298265, rs7823327, rs12055154, rs11107062, rs9858528, rs2166898, rs12119525, rs6962887, rs2735469, rs12153391, rs1113765, rs4875421, rs17038954, rs9395264, rs9977276, rs8097893, rs12820411, rs17264185, rs6999671, rs11855014, rs1348002, rs915506, rs4725061, rs738288, rs956796, rs4883972, rs6061231, rs2763273, rs4624820, rs11618507, rs3791673, rs1533269, rs929637, rs16939034, rs1552173, rs2117563, rs217181, rs7712162, rs692964, rs6435143, rs7181724, rs10283100, rs497273, rs960006, rs2219320, rs12519505, rs9309101, rs2345835, rs10997979, rs8103992, rs6971575, rs4325879, rs1461503, rs11612228, rs782930, rs867245, rs2679184, rs11750568, rs13133465, rs4141885, rs9825951, rs2682587, rs2326458, rs6691924, rs6137287, rs2057291, rs7261425, rs4326884, rs1861908, rs6658763, rs3802758, rs8042424, rs17783015, rs1244981, rs11783655, rs11156098, rs12863103, rs10779751, rs761391, rs9841435, rs7253628, rs16994718, rs11799609, rs4843367, rs17499117, rs2164968, rs12533079, rs926438, rs6544089, rs17181956, rs2120335, rs17250196, rs129963, rs731874, rs9291926, rs1797625, rs6952113, rs6754426, rs1409156, rs7544462, rs2961830, rs2715094, rs13150868, rs6584575, rs2596831, rs11616380, rs1478610, rs11634405, rs1053996, rs209918, rs10492364, rs2099745, rs3927536, rs1614303, rs2014467, rs2238300, rs992157, rs199515, rs7259684, rs1055144, rs4605213, rs2046158, rs4350272, rs7654571, rs11722554, rs11640018, rs4344931, rs4895801, rs10401193, rs2748483, rs13388725, rs3116168, rs2915404, rs3817428, rs12871822, rs958225, rs273945, rs11661645, rs13183624, rs4713902, rs894343, rs6887276, rs11624136, rs10083886, rs5757318, rs10460566, rs6446315, rs820848, rs2343240, rs2633761, rs870183, rs2531992, rs11835818, rs11708412, rs10059761, rs7782764, rs1171615, rs12597498, rs12329133, rs1004202, rs3818416, rs6563199, rs16964211, rs12137162, rs13416119, rs2224538, rs8117259, rs2275325, rs10744956, rs10759774, rs6813055, rs163071, rs300039, rs11683207, rs10817960, rs11057552, rs953199, rs16968242, rs6020202, rs3132297, rs1576900, rs833706, rs703985, rs12615742, rs2451948, rs2888893, rs3748394, rs2188177, rs10140101, rs11714558, rs2058092, rs10766065, rs1945237, rs7299326, rs996743, rs2164747, rs11100790, rs11861084, rs999599, rs11616067, rs888403, rs1966913, rs3750972, rs10048625, rs7170986, rs6596075, rs17330192, rs10972628, rs11198820, rs6511689, rs10962832, rs12454567, rs749234, rs17659078, rs4973429, rs2023693, rs1368380, rs6911389, rs8073177, rs17387330, rs11867943, rs11090631, rs6080830, rs14062, rs4243206, rs2247870, rs13113518, rs11950938, rs486359, rs1420023, rs17777628, rs11245515, rs8069300, rs12621643, rs17410035, rs7646824, rs6462432, rs6746356, rs1040941, rs4785393, rs6504389, rs1007358, rs4767473, rs7633464, rs2175513, rs936339, rs12914466, rs17075869, rs12513181, rs3169906, rs6688100, rs9327705, rs6829680, rs8028843, rs10995319, rs2059877, rs9405356, rs17113369, rs2167645, rs7097701, rs2272566, rs4746769, rs2815379, rs4674354, rs2034172, rs1014987, rs12669267, rs12731056, rs12228415, rs3026499, rs1544196, rs6794009, rs6762606, rs7162825, rs868489, rs11244750, rs11642612, rs17140875, rs2829941, rs2337143, rs11779459, rs1321666, rs6571772, rs12144094, rs4256170, rs3915129, rs7033940, rs7334755, rs833152, rs1199734, rs4868645, rs12190423, rs10820814, rs9929889, rs11236294, rs7743622, rs11731978, rs1346490, rs7284476, rs2737220, rs7007200, rs1571892

RECURSOS ADICIONALES:
Cómo afecta la altura a la salud
¿Por qué los holandeses son tan altos?

ACTUALIZACIÓN SEMANAL: 17 de enero de 2020

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