SUMMARY: This study discovered 41 new genetic variants that are associated with asthma, hay fever, eczema or a combination of the three.
DESCRIPTION: Asthma, hay fever, and eczema are common immunological diseases. All three conditions are linked to the body’s immune system response to an irritant or allergen, though their symptoms are different. Previous genome studies have discovered few variants that explain the genetics of these diseases. To expand this understanding, in this genome-wide association study, 346,545 individuals of European ancestry were analyzed to identify loci associated with asthma, hay fever, eczema, or some combination of the three. The study discovered 41 new loci, 16 of which are associated with all three diseases. However, some of these variants have significantly larger effects on one of the three diseases.
DID YOU KNOW? Avoiding the allergen altogether is the best way to prevent allergic reactions. Creams that contain corticosteroids can help against eczema. Nasal rinses and antihistamines are commonly prescribed against hay fever. [SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
ASTHMA-ASSOCIATED VARIANTS: rs62379371, rs6066184, rs9816107, rs2230624, rs9379828, rs3758212, rs7114923, rs2505504, rs7410883, rs4381563, rs3116590, rs12956924, rs10419921, rs61975764, rs1330303
WEEKLY UPDATE: August 9, 2019