photograph of eye

Thinning Cornea: Keratoconus (McComish, 2019)

STUDY TITLE: Association of Genetic Variation With Keratoconus 

SUMMARY: Discovery of 3 genetic regions associated with keratoconus, an eye condition characterized by thinning of the cornea.

OVERVIEW: The cornea is a thin, clear layer of tissue that covers the front of the eye. Like a car’s windshield, the cornea enables you to see clearly while protecting the inner parts of the eye. Keratoconus is a disease characterized by thinning and deformation of the cornea which can lead to blurry vision and nearsightedness. This genome-wide association study sought to discover variants associated with an increased risk of developing keratoconus. By examining the genetic information of nearly 6,000 individuals, researchers identified 3 genetic regions associated with the condition.

DID YOU KNOW? Long term use of contact lenses can lead to a reduced thickness of the cornea. Limiting the use of contact lenses to a maximum of 14-16 hours per day can help reduce this and other harmful effects. [SOURCE]

SAMPLE RESULTS: Learn more about the Nebula Research Library.

keratoconus sample results

KERATOCONUS-ASSOCIATED VARIANTS: rs138378, rs61876744, rs10831500

ADDITIONAL RESOURCES:
Cornea
Keratoconus

WEEKLY UPDATE: January 3, 2020

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