SUMMARY: Identification of genetic variants associated with migraines and synaptic function.
DESCRIPTION: Migraines are recurring headaches characterized by severe pain, nausea, and sensitivity to light and sound. They are the most common brain disorder, affecting 14% of adults. Currently, few genetic factors that associate with an increased predisposition to the condition have been found. This genome-wide association study identified 12 associated genetic variants, of which 5 are novel, by examining over 100,000 individuals of European ancestry. Most of the discovered variants are located in or near genes that play a role in synaptic function. Synapses are connections between brain cells that pass signals and enable communication.
DID YOU KNOW? Limiting stress, exercising, as well as sticking to a regular sleep and eating schedule may help prevent these headaches from occurring. [SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
MIGRAINE-ASSOCIATED VARIANTS: rs11172113, rs2651899, rs12134493, rs7577262, rs13208321, rs9349379, rs6478241, rs4379368, rs10504861, rs6790925, rs10915437, rs2274316
WEEKLY UPDATE: August 30, 2019