SUMMARY: Increased risk of schizophrenia is associated with a genetic variant in the intron of the MIR137 gene.
DESCRIPTION: Schizophrenia is a severe mental disorder that affects how a person thinks and behaves. Individuals with this condition may experience hallucinations, paranoia, and confused thoughts. It is known to be a heritable disorder, meaning it can be passed down from generation to generation. This study examined 51,695 individuals of European ancestry in order to identify genetic variants linked to the disorder. The strongest novel genetic variant associated with schizophrenia was in the intron of the MIR137 gene. The product of the MIR137 gene destabilizes mRNA, which is a molecule that is used as a template for the production of proteins. It is also a known regulator of neuronal development.
DID YOU KNOW? If this brain disorder runs in your family, you may be able to reduce your risk of developing the disease by avoiding drugs, having strong social ties, and managing your stress. [SOURCE]
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SCHIZOPHRENIA-ASSOCIATED VARIANTS: rs2021722, rs1625579, rs12966547, rs7914558, rs11191580, rs7004633, rs10503253, rs17662626
WEEKLY UPDATE: July 23, 2019