Long QT Syndrome (Lahrouchi, 2020)

Reports / By

STUDY TITLE: Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

SUMMARY: Identification of 3 genomic regions associated with long QT syndrome.

OVERVIEW: The heartbeat is controlled by electrical impulses which normally pause between beats. During that pause, the heart muscles recharge for the next beat. If this recharge takes too long, an electrocardiogram will show a long QT interval. People with long QT intervals can be affected by a fast and chaotic heartbeat which may cause fainting, seizures, and even death. This study compared 1,656 European or Japanese individuals with long QT syndrome to 9,890 healthy controls and found three associated genomic regions.

DID YOU KNOW? Some drugs can cause this syndrome. [SOURCE]

SAMPLE RESULTS: Learn more about the Nebula Research Library.

long qt syndrome sample results

LONG QT-ASSOCIATED VARIANTS: rs12143842, rs179405, rs17061696

ADDITIONAL RESOURCES:
What is long QT syndrome? (Video)
Genetic support foundation: Long QT syndrome

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WEEKLY UPDATE: June 16, 2020


About The Author

Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University. He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.