人脑模型

阿尔茨海默氏病(Dumitrescu,2020年)。

研究标题: Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

摘要: Identification of multiple regions of the genome associated with resilience to Alzheimer’s disease.

概述: Alzheimer’s disease is a form of dementia in which brain cells degenerate and die. The condition develops gradually, and over time affects memory, mood, thinking, and behavior. Alzheimer’s disease is quite common in seniors, potentially affecting up to half of those older than 85. However, while many people are affected by the degeneration of brain cells, not everyone develops cognitive impairments. These individuals are considered to have “asymptomatic” Alzheimer’s disease and little is known about the degree to which genetics influences whether an individual will be asymptomatic or show cognitive decline. This study examined the genomes of over 5,000 individuals to identify variants associated with resilience to developing symptoms of Alzheimer’s disease in the presence of degeneration in the brain. Researchers found multiple genomic regions that are potentially linked to resilience to Alzheimer’s disease. One region (tagged by the variant rs2571244) that showed a particularly strong association, harbors the gene known as ATP8B1. This gene plays a role in the transport of fat molecules inside cells, a function particularly important for the cells of the brain.

你知道吗? Increased education appears to correlate with a decreased risk of developing Alzheimer’s disease. Activities such as learning new languages and playing musical instruments can help keep your brain young! [来源]

样品结果: 了解更多关于 星云研究图书馆.

alzheimers disease sample results


ALZHEIMER’S DISEASE-ASSOCIATED VARIANTS: rs2571244, rs12580507, rs12127073, rs1840, rs7615592, rs12623748, rs982563, rs283562, rs9811609, rs3846121, rs1447462, rs11074247, rs11605469

补充资源:
Alzheimer’s disease (Video)
Alzheimer’s disease
What can you do to prevent Alzheimer’s? (Video)

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每周更新。 2020年9月7日


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